ProBiocin V

ProBiocin V is a clear to slightly hazy, water-soluble liquid obtained through the fermentation of Lactobacillus acidophilus supplemented with chicory oligosaccharide fructans. The process uses lysozyme-facilitated cell lysis to release potent postbiotic bacteriocin peptides. It is a multifunctional active designed for “treatment-first” formulations that require both antimicrobial protection and clinically proven skin-soothing benefits.

Key Features & Technical Benefits

  • Scalp Care Specialist: MIC testing against Malassezia furfur (the yeast associated with dandruff) shows performance comparable to Piroctone Olamine and superior to Climbazole.

  • Clinically Proven Redness Reduction: VISIA® complexion analysis over 6 weeks demonstrated a statistically significant reduction in “red area feature counts.” Regression data confirms the effect is a genuine treatment rather than a temporary artifact.

  • Scalp Health Improvement: In-vivo salon studies in shampoo and conditioner formats showed a “dramatic increase” in scalp moisturization and a significant decrease in erythema (redness).

  • Prebiotic Synergy: The use of chicory fructans in the growth medium ensures a high-quality lysate rich in metabolites that support a healthy skin microbiome.

Formulation & Handling

  • Thermal Sensitivity: Highly heat-sensitive. It must be incorporated during the cooling phase at temperatures below, register to find out

  • Preservation Strategy: Best deployed as part of a hurdle-approach strategy

  • Applications: Anti-dandruff shampoos, soothing scalp serums, and facial lotions targeting sensitive or red skin.

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Primary Function(s)
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INCI Name
Lactobacillus Ferment Lysate
CAS Number(s)
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Use Levels
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Free from Annex V or Preservative Free
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Application Type
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Cosmetic Science Criteria

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Green Criteria

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Natural Origin Index (ISO 16128)
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COSMOS Status
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Vegan
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Palm Status
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Palm Free
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Wild Harvested
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Biodegradability
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EWG Score
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Halal
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Upcycled
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Regulatory Status

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