Sensicare® M 4200

Sensicare® M 4200 (INCI: Gluconolactone, Sodium Benzoate, Calcium Gluconate) is a 100% natural, broad-spectrum antimicrobial powder. By combining a Polyhydroxy Acid (PHA) with a nature-identical organic acid salt, this multifunctional additive provides robust preservation while simultaneously improving skin hydration. It is the “clean-label” standard for formulators seeking compliance with the strictest environmental certifications.

Key Benefits and Performance

  • True Broad-Spectrum Mastery: Sensicare® M 4200 delivers proven efficacy across all major microbial categories:

    • Gram-negative bacteria: Including E. coli, Pseudomonas aeruginosa, and Salmonella.

    • Gram-positive bacteria: Including Staphylococcus aureus.

    • Fungi & Yeasts: Strong protection against Aspergillus niger and Candida albicans.

  • Multifunctional “Skin-Care” Preservation:

    • Moisturization: Gluconolactone acts as a humectant, significantly improving the moisture content of the skin.

    • Anti-Ageing: As a PHA, it provides gentle exfoliation and antioxidant benefits without the irritation associated with AHAs.

    • Binding Agent: In decorative cosmetics, it functions as an effective binder for compact powders.

  • Invisible Protection: As a white, water-soluble powder, it does not alter the scent, color, or transparency of the finished product, making it ideal for crystal-clear gels and high-end serums.

  • Thermal Stability: It maintains its integrity even at high processing temperatures, offering more flexibility than liquid organic acid blends.

Formulation Guidelines

  • The “pH Drift” Strategy: Gluconolactone slowly hydrolyzes into gluconic acid in water, which can cause a gradual drop in pH over time.

    • Buffering: It is critical to monitor pH stability; if a drop occurs, the system should be buffered using Sodium Lactate/Lactic Acid or Sodium Citrate/Citric Acid.

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Primary Function(s)
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INCI Name
Gluconolactone, Sodium Benzoate, Calcium Gluconate
CAS Number(s)
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Use Levels
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Free from Annex V or Preservative Free
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Application Type
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Synergistic blend

Cosmetic Science Criteria

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Green Criteria

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Natural Origin Index (ISO 16128)
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COSMOS Status
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Vegan
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Palm Status
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Palm Free
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Wild Harvested
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Biodegradability
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EWG Score
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Halal
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Upcycled
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Regulatory Status

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