Neolone® BioG Preservative

NEOLONE® BioG is one of the rare naturally derived ingredients formally recognized as a preservative in Annex V of the EU Cosmetics Regulation. It is synthesized from three natural building blocks: L-arginine (amino acid), Lauric acid (coconut/palm), and Ethanol (sugar fermentation). Its safety is backed by extensive SCCS toxicology data, confirming it is non-irritating and non-sensitizing at recommended levels.

Key Benefit: A “Regulatory Gold Standard” natural preservative that offers a well-characterized cationic mechanism of action to induce rapid loss of microbial cell viability.

Performance & Biological Activity

  • Antimicrobial Mechanism: The cationic molecular structure disrupts bacterial cell membrane potential and alters permeability, preventing the growth of Gram-positive/negative bacteria, yeasts, and molds.

  • Environmental Profile: Readily biodegradable, non-bioaccumulative, and low aquatic toxicity.

  • Sensory Neutrality: Odorless and has no influence on the final product’s color or fragrance at recommended use levels.

Formulation & Compatibility Guidance

As a cationic molecule, NEOLONE® BioG requires precise formulation to avoid precipitation or stability failures.

Category Compatibility Status
Optimal pH Below pH ..register to find out
Incompatible Anionic thickeners (Carbomer, Xanthan, CMC, Carrageenan) and Anionic surfactants (SLS/SLES))
Compatible Non-ionic/Cationic thickeners, Alkyl Glucosides, CAPB, and Cationic surfactants
Synergies Validated with Sodium Benzoate, Sodium Anisate, 1,2-Hexanediol, and Gluconolactone

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Primary Function(s)
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INCI Name
Ethyl lauroyl arginate HCl, Glycerin
CAS Number(s)
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Use Levels
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Free from Annex V or Preservative Free
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Application Type
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Cosmetic Science Criteria

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Green Criteria

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Natural Origin Index (ISO 16128)
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COSMOS Status
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Vegan
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Palm Status
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Palm Free
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Wild Harvested
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Biodegradability
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EWG Score
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Halal
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Upcycled
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Regulatory Status

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