NEOLONE® BioG is one of the rare naturally derived ingredients formally recognized as a preservative in Annex V of the EU Cosmetics Regulation. It is synthesized from three natural building blocks: L-arginine (amino acid), Lauric acid (coconut/palm), and Ethanol (sugar fermentation). Its safety is backed by extensive SCCS toxicology data, confirming it is non-irritating and non-sensitizing at recommended levels.
Key Benefit: A “Regulatory Gold Standard” natural preservative that offers a well-characterized cationic mechanism of action to induce rapid loss of microbial cell viability.
Performance & Biological Activity
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Antimicrobial Mechanism: The cationic molecular structure disrupts bacterial cell membrane potential and alters permeability, preventing the growth of Gram-positive/negative bacteria, yeasts, and molds.
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Environmental Profile: Readily biodegradable, non-bioaccumulative, and low aquatic toxicity.
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Sensory Neutrality: Odorless and has no influence on the final product’s color or fragrance at recommended use levels.
Formulation & Compatibility Guidance
As a cationic molecule, NEOLONE® BioG requires precise formulation to avoid precipitation or stability failures.
| Category | Compatibility Status |
| Optimal pH | Below pH ..register to find out |
| Incompatible | Anionic thickeners (Carbomer, Xanthan, CMC, Carrageenan) and Anionic surfactants (SLS/SLES)) |
| Compatible | Non-ionic/Cationic thickeners, Alkyl Glucosides, CAPB, and Cationic surfactants |
| Synergies | Validated with Sodium Benzoate, Sodium Anisate, 1,2-Hexanediol, and Gluconolactone |