Sepicide G

Sepicide G is a natural-origin preservation system based on Ethyl Lauroyl Arginate HCl (LAE®) in a glycerin carrier. LAE is an amino acid-derived cationic surfactant synthesized from three natural building blocks: L-arginine, lauric acid (derived from palm or coconut oil), and fermented ethanol. It represents a biodegradable, sustainable solution for modern microbial control in personal care.

Key Benefits and Performance

  • Broad-Spectrum Activity: Demonstrates high efficacy at low concentrations against Gram-positive and Gram-negative bacteria, yeasts, and moulds via cell membrane disruption.

  • pH-Independent Performance: Maintains stable antimicrobial activity across a wide pH range 

  • Targeted Efficacy: Highly active against Malassezia furfur, supporting anti-dandruff and scalp-health claims.

  • Multi-Active Profile: Offers documented anti-acne and deodorizing properties, while its cationic nature provides skin and hair conditioning/smoothing effects.

Formulation Guidelines

  • Regulatory Limits: Maximum 0.4% active substance in cosmetic products; 0.15% in mouthwashes (EU Annex V). Note: Prohibited in lip, oral (except mouthwash), and spray products.

  • Ionic Considerations: As a cationic ingredient, it may interact with anionic surfactants or thickeners, which can lower efficacy.

  • Formulation Stability: Best used in non-ionic or cationic systems, or combined with other agents for synergistic effects in complex anionic environments.

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Primary Function(s)
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INCI Name
Ethyl lauroyl arginate HCl, Glycerin
CAS Number(s)
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Use Levels
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Free from Annex V or Preservative Free
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Application Type
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Cosmetic Science Criteria

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Green Criteria

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Natural Origin Index (ISO 16128)
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COSMOS Status
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Vegan
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Palm Status
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Palm Free
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Wild Harvested
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Biodegradability
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EWG Score
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Halal
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Upcycled
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Regulatory Status

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