Leucidal® Liquid is a patented (US Patent 10,159,708) antimicrobial produced by fermenting Raphanus sativus (radish root) with Leuconostoc kimchii. During this process, the bacteria produce antimicrobial peptides (bacteriocins) and acidify the environment, creating a dual mechanism of protection. Post-fermentation, willow bark extract is used to facilitate cell lysis, resulting in a filtrate rich in naturally occurring salicylates.
Key Features & Technical Benefits
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Microbiome Rebalancing: 16S rRNA sequencing shows it selectively reduces Propionibacterium while supporting beneficial Staphylococcus and Corynebacterium populations.
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Multifunctional Efficacy:
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Anti-Inflammatory: IL-6 ELISA assay demonstrated significant anti-inflammatory potential.
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Skin Health: Clinically proven to reduce TEWL, increase skin density (ultrasound imaging), and promote wound healing (scratch assay).
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Antioxidant: ORAC assay confirms antioxidant capacity.
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“Maskne” Treatment: Effectively reduces total aerobic bacteria, S. aureus, and C. acnes on face mask substrates at maximum inclusion level.
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Natural Salicylates: Contains salicylate salts/esters rather than free salicylic acid, a key regulatory distinction for EU Annex III and V compliance.
Formulation & Handling
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Cationic Nature: Slightly cationic; may complex with anionic thickeners, potentially causing viscosity loss. Adding extra thickener or incorporating it at the end of the process can compensate.
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Stability: pH range , register to find out. Best added during the cooling phase below 40°C.
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Suggested Use Level: register to find out
